Search scope:
排序: Display mode:
Identification of pollution sources in rivers using a hydrodynamic diffusion wave model and improved
Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1685-1
● A hydrodynamic-Bayesian inference model was developed for water
Keywords: Identification of pollution sources Water quality restoration Bayesian inference Hydrodynamic model
Study on hydrodynamic and synthetic water quality model for river networks
Zhang Mingliang,Shen Yongming
Strategic Study of CAE 2008, Volume 10, Issue 10, Pages 78-83
Keywords: Preissmann implicit scheme river networks hydrodynamic model water quality model WASP model
Development of a hydrodynamic model and the corresponding virtual software for dual-loop circulating
Shanwei Hu, Xinhua Liu
Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3, Pages 579-590 doi: 10.1007/s11705-020-1953-6
Keywords: multi-loop circulating fluidized bed mathematical modeling energy minimization multiscale virtual fluidization mesoscale structure
Nazim Abdul NARIMAN, Tom LAHMER, Peyman KARAMPOUR
Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 2, Pages 303-323 doi: 10.1007/s11709-018-0462-x
Keywords: massed foundation hydrodynamic pressure Box-Behnken method meta model Sobol’s sensitivity indices
Jingyu WANG,Hongwei FANG,Guojian HE,Lei HUANG
Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 6, Pages 845-853 doi: 10.1007/s11783-014-0708-3
Keywords: distribution coefficient Daya Bay hydrodynamic sediment transport radionuclide transport
Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 6, Pages 854-873 doi: 10.1007/s11705-022-2156-0
Keywords: annular centrifugal extractor hydrodynamic characteristics structure optimization the latest application
Numerical analysis of hydrodynamic process of circular-translational-moving polishing (CTMP)
ZHAI Wenjie, LIU Changxiong, LIANG Yingchun
Frontiers of Mechanical Engineering 2008, Volume 3, Issue 4, Pages 441-448 doi: 10.1007/s11465-008-0074-6
Keywords: numerical analysis practical CTMP circular-translational-moving polishing CTMP different
Haifeng JIA, Shuo WANG, Mingjie WEI, Yansong ZHANG
Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 2, Pages 255-265 doi: 10.1007/s11783-010-0279-x
Keywords: peri-urban river coupled hydrodynamic-water quality modeling scenario analysis river rehabilitation
Stormwater treatment: examples of computational fluid dynamics modeling
Gaoxiang YING, John SANSALONE, Srikanth PATHAPATI, Giuseppina GAROFALO, Marco MAGLIONICO, Andrea BOLOGNESI, Alessandro ARTINA
Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5, Pages 638-648 doi: 10.1007/s11783-012-0442-7
Keywords: stormwater unit operations and processes (UOPs) hydrodynamic separation filtration adsorption computationalfluid dynamics (CFD) turbulence modeling discrete phase model particle separation detention/retention
Haoxuan Zheng, Ying Zheng, Jesse Zhu
Engineering 2022, Volume 19, Issue 12, Pages 180-198 doi: 10.1016/j.eng.2022.04.027
Hydrodynamic cavitation is considered to be a promising technology for process intensification, dueIn the past decade, advancements have been made in the fundamental understanding of hydrodynamic cavitationTwo types of hydrodynamic cavitation reactors—namely, stationary and rotational—are comparedThe design parameters of a hydrodynamic cavitation reactor and reactor performance at the laboratoryThe unique features of hydrodynamic cavitation have been widely applied to various chemical reactions
Keywords: Hydrodynamic cavitation Cavitation nuclei Hydroxyl radicals Stationary/rotational hydrodynamic cavitation
Method of internal 3D flow field numerical simulation for hydrodynamic torque converter
SHANG Tao, ZHAO Dingxuan, ZHANG Yuankun, GUO Xiangen, SHI Xiangzhong
Frontiers of Mechanical Engineering 2008, Volume 3, Issue 1, Pages 86-90 doi: 10.1007/s11465-008-0012-7
Keywords: velocity distribution calculation numerical simulation three-element centrifugal converter
Theory and Practice of Hydrodynamic Reconstruction in Plain River Networks Article
Hongwu Tang, Saiyu Yuan, Hao Cao
Engineering 2023, Volume 24, Issue 5, Pages 202-212 doi: 10.1016/j.eng.2022.01.015
Keywords: Plain river network Water security problems Hydrodynamic reconstruction Multi-objective Integrated
Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10, Pages 1484-1502 doi: 10.1007/s11705-023-2331-y
Keywords: polysulfone blend modification ultrafiltration membrane formation hydrodynamics poly(ethylene-co-vinyl alcohol) copolymer
Floating forest: A novel breakwater-windbreak structure against wind and wave hazards
Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 5, Pages 1111-1127 doi: 10.1007/s11709-021-0757-1
Keywords: floating structure breakwater windbreak hydrodynamic CFD
Optimized human factor IX expression cassettes for hepatic-directed gene therapy of hemophilia B
Ru Zhang,Qiang Wang,Lin Zhang,Saijuan Chen
Frontiers of Medicine 2015, Volume 9, Issue 1, Pages 90-99 doi: 10.1007/s11684-015-0390-2
Gene therapy provides a potential cure for hemophilia B, and significant progress has been achieved in liver-directed gene transfer mediated by adeno-associated viral vectors. Recent clinical trials involving the use of a self-complementary adeno-associated virus serotype 8-human codon-optimized factor IX (AAV8-hFIXco) vector demonstrated encouraging efficacy with hFIX expression stabilized at 1% to 6% of normal level in patients, but safety concerns related to high vector doses are still present. Thus, further improvement of AAV vectors and hFIX expression cassette may positively contribute to the ultimate success of hemophilia B gene therapy. In this study, to obtain a higher expression level of hFIX that potentiates the coagulant capacity of recipients, human FIX expression vector was optimized by upgrading the codon adaption index and adjusting the GC content, inserting a Kozak sequence (GCCACC), and introducing a gain-of-function mutation, R338L (FIX Padua). The efficiency of the published and the presently constructed cassettes was compared through in vivo screening. In addition, the regulatory elements that control the FIX gene expression in these cassettes were screened for liver-specific effectiveness. Among all the constructed cassettes, scAAV-Pre-hFIXco-SIH-R338L, which was the construct under the control of the prothrombin enhancer and prealbumin promoter, resulted in the highest level of coagulant activity, and the expression levels of two constructed cassettes (scAAV-Chi-hFIXco-SIH-R338L and scAAV-Pre-hFIXco-SIH-R338L) were also higher than that of the published cassette (scAAV-LP1-hFIXco-SJ). In summary, our strategies led to a substantial increase in hFIX expression at the protein level or a remarkably elevated coagulant activity. Thus, these reconstructs of hFIX with AAV vector may potentially contribute to the creation of an efficacious gene therapy of hemophilia B.
Keywords: factor IX hemophilia B liver-specific regulatory elements hydrodynamic gene transfer
Title Author Date Type Operation
Identification of pollution sources in rivers using a hydrodynamic diffusion wave model and improved
Journal Article
Study on hydrodynamic and synthetic water quality model for river networks
Zhang Mingliang,Shen Yongming
Journal Article
Development of a hydrodynamic model and the corresponding virtual software for dual-loop circulating
Shanwei Hu, Xinhua Liu
Journal Article
Uncertainty quantification of stability and damage detection parameters of coupled hydrodynamic-ground
Nazim Abdul NARIMAN, Tom LAHMER, Peyman KARAMPOUR
Journal Article
Recent progress in hydrodynamic characteristics research and application of annular centrifugal extractors
Journal Article
Numerical analysis of hydrodynamic process of circular-translational-moving polishing (CTMP)
ZHAI Wenjie, LIU Changxiong, LIANG Yingchun
Journal Article
Scenario analysis of water pollution control in the typical peri-urban river using a coupled hydrodynamic-waterquality model
Haifeng JIA, Shuo WANG, Mingjie WEI, Yansong ZHANG
Journal Article
Stormwater treatment: examples of computational fluid dynamics modeling
Gaoxiang YING, John SANSALONE, Srikanth PATHAPATI, Giuseppina GAROFALO, Marco MAGLIONICO, Andrea BOLOGNESI, Alessandro ARTINA
Journal Article
Recent Developments in Hydrodynamic Cavitation Reactors: Cavitation Mechanism, Reactor Design, and Applications
Haoxuan Zheng, Ying Zheng, Jesse Zhu
Journal Article
Method of internal 3D flow field numerical simulation for hydrodynamic torque converter
SHANG Tao, ZHAO Dingxuan, ZHANG Yuankun, GUO Xiangen, SHI Xiangzhong
Journal Article
Theory and Practice of Hydrodynamic Reconstruction in Plain River Networks
Hongwu Tang, Saiyu Yuan, Hao Cao
Journal Article
antifouling, and permeation properties of polysulfone ultrafiltration membrane: thermodynamic and formation hydrodynamic
Journal Article
Floating forest: A novel breakwater-windbreak structure against wind and wave hazards
Journal Article